20.septembra 2013.g. u amfiteatru A2 Farmaceutskog fakulteta Univerziteta u Beogradu, Vojvode Stepe 450
SIMULATIONS PLUS SOFTWARE: ITS APPLICATIONS IN VARIOUS ASPECTS OF PHARMACY AND CHEMISTRY
– S E M I N A R –
Faculty of Pharmacy, University of Belgrade
September 20, 2013.
ORGANISERS:
Faculty of Pharmacy, University of Belgrade
Simulations Plus, CA, USA
Serbian Chemical Society
SCOPE:
The seminar will focus on applications of Simulations Plus prediction and modeling programs in various aspects of pharmacy and chemistry: medicinal chemistry and drug design, applied chemistry, pharmacology, pharmacokinetics, pharmaceutical technology, and toxicology.
ORGANISING COMMITTEE:
Prof. Dr. Slavica Erić, Associate professor at Faculty of Pharmacy, University of Belgrade, Serbia
Dr. Robert Fraczkiewicz, Team Leader at Simulations Plus, Lancaster, California, USA
Mr. Branko Drakulić, Research scientist at Department of Chemistry-IChTM, University of Belgrade, Serbia
Prof. Dr. Slavica Ražić, Vice-president of Serbian Chemical Society, Professor at Faculty of Pharmacy, University of Belgrade, Serbia
VENUE:
Faculty of Pharmacy, University of Belgrade, Vojvode Stepe 450, Belgrade, Serbia
DATE:
Friday, September 20, 2013, 1000-1600
SPEAKERS:
Dr. Robert Fraczkiewicz, Simulations Plus, Lancaster, California, USA
Mr. Branko Drakulić, Department of Chemistry-IChTM, University of Belgrade, Serbia
Dr. Irena Homšek, Galenika a.d., Belgrade, Serbia
Prof. Dr. Slavica Erić, Department of Pharmaceutical Chemistry, Faculty of Pharmacy,
University of Belgrade, Serbia
Dr. Ivana Kocić, Galenika a.d., Belgrade, Serbia
Doc. Dr. Sandra Grbić, Department of Pharmaceutical Technology and Cosmetology,
Faculty of Pharmacy, University of Belgrade, Serbia
Prof. Dr. Mirjana Đukić, Department of Toxicology, Faculty of Pharmacy, University of
Belgrade, Serbia
PROGRAMME:
10:00 Introduction
Organising committee
10:15 Overview of Simulations Plus Software
Dr. Robert Fraczkiewicz (Simulations Plus, Lancaster, California, USA)
10:30 Using Simulations Plus’ ADMET Predictor as an Accompanying Tool in QSAR/LFER Modeling: Case Studies
Mr. Branko Drakulić (Department of Chemistry-IChTM, University of Belgrade, Serbia)
11:00 Application of ADMET Predictor in Biopharmaceutical Characterization of Telmisartan
Dr. Irena Homšek (Galenika a.d., Belgrade, Serbia)
11:30 Application of ADMET Modeler to the Development of Classification Models for Drug Transport by P-glycoprotein and Breast Cancer Resistance Protein
Prof. Dr. Slavica Erić (Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of
Belgrade, Serbia)
12:00 Coffee Break
12:45 The Art of Predicting Ionization Constants
Dr. Robert Fraczkiewicz (Simulations Plus, Lancaster, California, USA)
13:45 GastroPlus Simulations of Levothyroxine Absorption from Immediate Release Tablets: the investigation of a Possibility of Biowaiver
Ivana Kocić (Galenika a.d., Belgrade; Serbia)
14:15 Computer Aided Biopharmaceutical Characterization: GastroPlus Absorption Simulation
Doc. Dr. Sandra Grbić (Department of Pharmaceutical Technology and Cosmetology, Faculty of Pharmacy, University of Belgrade, Belgrade, Serbia)
14:45 Usefulness of Computational Methods in Understanding of Peroxidase Activity of Cytochrome C Influenced by Xenobiotics
Prof. Dr. Mirjana Đukić (Department of Toxicology, Faculty of Pharmacy, University of Belgrade, Serbia)
15.00 Discussion